pentobarbital will minimize the extent or result of fentanyl by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Carefully. Coadministration of fentanyl with CYP3A4 inducers may lead to a reduce in fentanyl plasma concentrations, not enough efficacy or, probably, improvement of a withdrawal syndrome in the clien… Read More